- Following his victory in Malaysia, Andrea Dovizioso (Ducati Team) arrives at the final race of the year with a 21-point deficit in the World Championship classification. If Dovizioso wins the race in Valencia, then Marc Márquez will need to finish 11th or better to take the world title.
- Since the motorcycle Grand Prix World Championship series was introduced in 1949 there have been 17 occasions previously that the premier class title has been decided at the final race of the year.
- Only three riders have overturned a points deficit in the final race of the year to become premier class world champion: Wayne Rainey in 1992, Nicky Hayden in 2006 and Jorge Lorenzo in 2015.
- The largest deficit any rider has overturned at the final race of the year to win the premier class world title is eight points, done by the late, great Nicky Hayden in 2006.
- If Márquez wins the championship, he will be the youngest ever rider to win four premier class world titles and the youngest rider to win six world titles across all classes.
- If Andrea Dovizioso wins the championship, he will be the oldest champion of the MotoGP era, and the oldest premier-class champion since Mick Doohan in 1998.